Publications highlights

Wölk, M., Prabutzki, P., & Fedorova, M. (2023). Analytical Toolbox to Unlock the Diversity of Oxidized Lipids. Accounts of Chemical Research, 56(7), 835-845.

Nat Methods

Ni, Z., Wölk, M., Jukes, G., Mendivelso Espinosa, K., Ahrends, R., Aimo, L., … & O’Donnell, VB., Fedorova, M. (2023). Guiding the choice of informatics software and tools for lipidomics research applications. Nature Methods, 20(2), 193-204.

Nat Commun

Criscuolo, A., Nepachalovich, P., Garcia-del Rio, D. F., Lange, M., Ni, Z., Baroni, M., … & Fedorova, M. (2022). Analytical and computational workflow for in-depth analysis of oxidized complex lipids in blood plasma. Nature Communications, 13(1), 6547.

2023

☆  da Silva KM, Wölk M, Nepachalovich P, Iturrospe E, Covaci A, van Nuijs ALN, Fedorova M (2023) Investigating the Potential of Drift Tube Ion Mobility for the Analysis of Oxidized Lipids. Anal Chem. 95(36):13566-13574. DOI: 10.1021/acs.analchem.3c02213
☆  
Witt A, Mateska I, Palladini A, Sinha A, Wölk M, Harauma A, Bechmann N, Pamporaki C, Dahl A, Rothe M, Kopaliani I, Adolf C, Riester A, Wielockx B, Bornstein SR, Kroiss M, Peitzsch M, Moriguchi T, Fedorova M, Grzybek M, Chavakis T, Mirtschink P, Alexaki VI. (2023) Fatty acid desaturase 2 determines the lipidomic landscape and steroidogenic function of the adrenal gland. Sci. Adv. 21;9(29):eadf6710. DOI: 10.1126/sciadv.adf6710.

☆  Wölk M, Prabutzki P, Fedorova M. (2023) Analytical Toolbox to Unlock the Diversity of Oxidized Lipids. Acc Chem Res. 56(7):835-845. DOI: 10.1021/acs.accounts.2c00842.

☆  Ni Z, Wölk M, Jukes G, Mendivelso Espinosa K, Ahrends R, Aimo L, Alvarez-Jarreta J, Andrews S, Andrews R, Bridge A, Clair GC, Conroy MJ, Fahy E, Gaud C, Goracci L, Hartler J, Hoffmann N, Kopczyinki D, Korf A, Lopez-Clavijo AF, Malik A, Ackerman JM, Molenaar MR, O’Donovan C, Pluskal T, Shevchenko A, Slenter D, Siuzdak G, Kutmon M, Tsugawa H, Willighagen EL, Xia J, O’Donnell VB and Fedorova M. (2023) Guiding the choice of informatics software and tools for lipidomics biomedical research applications. Nat Methods. 20(2):193-204. DOI: 10.1038/s41592-022-01710-0.

2022

☆  Criscuolo A, Nepachalovich P, Garcia-Del Rio DF, Lange M, Ni Z, Baroni M, Cruciani G, Goracci L, Blüher M, Fedorova M. (2022) Analytical and computational workflow for in-depth analysis of oxidized complex lipids in blood plasma. Nat Commun. 13:6547. DOI: 10.1038/s41467-022-33225-9

☆  Mishima E, Ito J, Wu Z, Nakamura T, Doll S, Tonnus W, Nepachalovich P, Eggenhofer E, Aldrovandi M, Henkelmann B, Yamada K, Wanninger J, Wahida A, Zilka O, Sato E, Feederle R, Hass D, Maida A, Dias Mourão AS, Linkermann A, Geissler EK, Nakagawa K, Abe T, Fedorova M, Proneth B, Pratt DA, Conrad M. (2022) A non-canonical vitamin K cycle is a potent ferroptosis suppressor. Nature. 608(7924): 778-783. DOI: 10.1038/s41586-022-05022-3

☆  Freitas FP, Nepachalovich P, Puentes L, Zilka O, Inague A, Lorenz S, Kunz V, Nehring H, Xavier da Silva TN, Chen Z, Doll S, Schmitz W, Imming P, Miyamoto S, Klein-Seetharaman J, Kumar L, Genaro-Mattos TC, Mirnics K, Meierjohann S, Kroiss M, Weigand I, Bommert K, Bargou R, Garcia-Saez A, Pratt D, Fedorova M, Wehmann A, Horling A, Bornkamm G, Conrad M, Angeli JPF. (2022) 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis. Research Square. DOI: 10.21203/rs.3.rs-943221/v1.

☆  Trautenberg LC, Fedorova M, Brankatschk M. (2022) Insulin regulates systemic lipid traffic in starving animals. BioRxiv. DOI: 10.1101/2022.05.09.491148.

☆  McDonald JG, Ejsing CS, Kopczynski D, Holčapek M, Aoki J, Arita M, Arita M, Baker ES, Bertrand-Michel J, Bowden JA, Brügger B, Ellis SR, Fedorova M, Griffiths WJ, Han X, Hartler J, Hoffmann N, Koelmel JP, Köfeler HC, Mitchell TW, O’Donnell VB, Saigusa D, Schwudke D, Shevchenko A, Ulmer CZ, Wenk MR, Witting M, Wolrab D, Xia Y, Ahrends R, Liebisch G, Ekroos K. (2022) Introducing the Lipidomics Minimal Reporting Checklist. Nat Metabolism. 4(9): 1086-1088. DOI: 10.1038/s42255-022-00628-3.

☆  Wölk M, Milkovska-Stamenova S, Fedorova M, Hoffmann R. (2022) Variations in the milk lipidomes of two dairy cow herds fed hay- or silage-based diets over a full year. Food Chemistry. 390: 133091. DOI: 10.1016/j.foodchem.2022.133091.

☆  Marisa I, Asnicar D, Matozzo V, Parolini M, Brianese N, Fedorova M, Hoffmann R, Sheehanf D, Marin MG. (2022) Zinc oxide, titanium dioxide and C60 fullerene nanoparticles, alone and in mixture, differently affect biomarker responses and proteome in the clam Ruditapes philippinarum. Sci Total Environ. 838, 155873. DOI: 10.1016/j.scitotenv.2022.155873.

☆  Sochorova M, Vavrova K, Fedorova M, Ni Z, Slenter D, Kutmon M, Willighagen EL, Letsiou S, Töröcsik D, Marchetti-Deschmann, Zoratto S, Kremslehner Ch, Gruber F. (2022) Research techniques Made simple: Lipidomics analysis in skin research. J Invest Dermatol. 142, 4-11. DOI: 10.1016/j.jid.2021.09.017

2021

Å☆  Gladine C and Fedorova M. (2021) The clinical translation of eicosanoids and other oxylipins, although challenging, should be actively pursued. J Mass Spectrom Adv Clin Lab. 21: 27-30. DOI: 10.1016/j.jmsacl.2021.08.003.

☆  Köfeler HC, Eichmann TO, Ahrends R, Bowden JA, Danne-Rasche N, Dennis EA, Fedorova M, Griffiths WJ, Han X, Hartler J, Holčapek M, Jirásko R, Koelmel JP, Ejsing CS, Liebisch G, Zhixu N, O’Donnell VB, Quehenberger O, Schwudke D, Shevchenko A, Wakelam MJO, Wenk MR, Wolrab D, Ekroos K. (2021) Quality control requirements for the correct annotation of lipidomics data. Nat Commun. 12, 4771. DOI: 10.1038/s41467-021-24984-y.

☆  Koelmel JP, Aristizabal-Henao JJ, Ni Z, Fedorova M, Kato S, Otoki Y, Nakagawa K, Lin EZ, Godri Pollitt KJ, Vasiliou V, Guingab JD, Garrett TJ, Williams TL, Bowden JA, Penumetcha M. (2021) A Novel Technique for Redox Lipidomics Using Mass Spectrometry: Application on Vegetable Oils Used to Fry Potatoes. J Am Soc Mass Spectrom. 7, 32(7):1798-1809. DOI: 10.1021/jasms.1c00150.

☆  Kyle JE, Aimo L, Bridge AJ, Clair G, Fedorova M, Helms JB, Molenaar MR, Ni Z, Orešič M, Slenter D, Willighagen E, Webb-Robertson BJM. (2021) Interpreting the Lipidome – Bioinformatic Approaches to Embrace the Complexity. Metabolomics. 17, 55. DOI: 10.1007/s11306-021-01802-6.

☆  Griesser E, Vemula V, Mónico A, Pérez-Sala D, Fedorova M. (2021) Dynamic posttranslational modifications of cytoskeletal proteins unveil hot spots under nitroxidative stress. Redox Biol. 44, 102014. DOI: 10.1016/j.redox.2021.102014.

☆  Aldrovandi M, Fedorova M *, Conrad M *. (2021) Juggling with Lipids, a Russian Roulette. Trends Endocrinol Metab. 32 (7): 463-473. DOI: 10.1016/j.tem.2021.04.012

☆  Lange M, Wagner PV, Fedorova M. (2021) Lipid composition dictates the rate of lipid peroxidation in artificial lipid droplets. Free Radic Res. 19;1-12. DOI: 10.1080/10715762.2021.1898603.

☆  Lange M, Angelidou G, Ni Z, Criscuolo A, Schiller J, Blüher, Fedorova M. (2021) AdipoAtlas: a reference lipidome of human white adipose tissue. Cell Rep Med. 2(10): 100407. DOI: 10.1016/j.xcrm.2021.100407.

☆  Ravandeh M, Coliva G, Kahlert H, Azinfar A, Helm C, Fedorova M, Wende K. (2021) Protective role of sphingomyelin in eye lens cell membrane model against oxidative stress. Biomolecules. 11(2): 276. DOI: 10.3390/biom11020276.

☆  Gaud C, Sousa BC, Nguyen A, Fedorova M, Ni Z, O’Donnell VB, Wakelam MJO, Andrews S, Lopez-Clavijo AF. (2021) BioPAN: a web-based tool to explore mammalian lipidome metabolic pathways on LIPID MAPS. F1000 Research.10:4.  DOI: 10.12688/f1000research.28022.2.

2020

☆  Liebisch G, Fahy E, Aoki J, Dennis EA, Durand T, Ejsing Ch, Fedorova M, Feussner I, Griffiths WJ, Koefeler H, Merrill AH, Murphy RC, O’Donnell VB, Oskolkova OV, Subramaniam S, Wakelman M, Spener F. (2020) Update on LIPID MAPS Classification, Nomenclature and Shorthand Notation for MS-derived Lipid Structures. Journal of Lipid Research. 61(12):1539-1555. DOI: 10.1194/jlr.S120001025.

☆ Ni Z, Fedorova M. (2020) LipidLynxX: a data transfer hub to support integration of large scale lipidomics datasets. BioRxiv. DOI: 10.1101/2020.04.09.033894.

☆  Coliva G, Lange M, Colombo S, Chervet JP, Domingues MR, Fedorova M. (2020) Sphingomyelins prevent propagation of lipid peroxidation – LC-MS/MS evaluation of inhibition mechanism. Molecules. 25(8): 1925. DOI: 10.3390/molecules25081925.

☆  Lange M, Fedorova M.(2020) Evaluation of lipid quantification accuracy using HILIC and RPLC MS on the example of NIST® SRM® 1950 Metabolites Human Plasma. Anal Bioanal Chem. 412(15): 3573-3584. DOI: 10.1007/s00216-020-02576-x.

☆  Jannuzzi AT, Arslan S, Yilmaz AM, Sari G, Belen H, Mendez L, Fedorova M, Agra KY, Karademir Yilmaz B, Alpertunga B. (2020) Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib. Redox Biol. 32: 101502. DOI: 10.1016/j.redox.2020.101502.

☆  Criscuolo A, Zeller M, Fedorova M. (2020) Evaluation of lipid in-source fragmentation on different orbitrap-based mass spectrometers. J Am Soc Mass Spectrom. 31(2): 463-466. DOI: 10.1021/jasms.9b00061.

☆  Bhandari DR, Coliva G, Fedorova M, Spengler B. (2020) Single Cell Analysis by High-Resolution Atmospheric-Pressure MALDI MS Imaging. Methods Mol Biol. 2064:103-111. DOI: 10.1007/978-1-4939-9831-9_8.

☆  Striesow J, Lackmann JW, Ni Z, Wenske S, Weltmann KD, Fedorova M, von Woedtke T, Wende K (2020) Oxidative modification of skin lipids by cold atmospheric plasma (CAP): A stanardizable approach using RP-LC/MS 2 and DI-ESI/MS 2. Chem Phys Lipids. 226:104786. DOI: 10.1016/j.chemphyslip.2019.104786.

2019

☆  Cruciani G, Domingues P, Fedorova M, Galli F, Spickett CM. (2019) Redox lipidomics and adductomics – Advanced analytical strategies to study oxidized lipid-protein adducts. Free Radic Biol Med. 144: 1-5. DOI: 10.1016/j.freeradbiomed.2019.07.027.

☆  Kreiter J, Rupprecht A, Zimmermann L, Moschinger M, Rokitskaya TI, ANtonenko YN, Gille L, Fedorova M, Pohl EE. (2019) Molecular mechanisms responsible for pharmacological effects of genipin on mitochondrial proteins. Biophys J.117(10): 1845-1857. DOI: 10.1016/j.bpj.2019.10.021

☆  Ni Z, Sousa BC, Colombo S, Afonso CB, Melo T, Pitt AR, Spickett CM, Domingues P, Domingues MR, Fedorova M, Criscuolo A (2019) Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS. Free Radical Biology and Medicine. 144: 156-166. DOI: 10.1016/j.freeradbiomed.2019.06.013.

☆  Colombo S, Criscuolo A, Zeller M, Fedorova M, Domingues MR, Domingues P (2019) Analysis of oxidized and glycated aminophospholipids: Complete structural characterization by C30 liquid chromatography-high resolution tandem mass spectrometry. Free Radic Biol Med. 144: 144-155. DOI: 10.1016/j.freeradbiomed.2019.05.025.

☆  Campos-Pinto I, Mendez L, Schouten J, Wilkins J, Fedorova M, Pitt AR, Davis P, Spickett CM (2019) Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies. Free Radic Biol Med. 144: 234-244. DOI: 10.1016/j.freeradbiomed.2019.05.008.

☆  Ni Z, Goracci L, Cruciani G, Fedorova M (2019) Computational solutions in redox lipidomics – current strategies and future perspectives. Free Radic Biol Med. 144: 110-123. DOI: 10.1016/j.freeradbiomed.2019.04.027.

☆  Criscuolo A, Zeller M, Cook K, Angelidou G, Fedorova M (2019) Rational selection of reverse phase columns for high throughput LC-MS lipidomics. Chem Phys Lipids. 221: 120-127. DOI: 10.1016/j.chemphyslip.2019.03.006.

☆  Coliva G, Duarte S, Perez-Sala D, Fedorova M. (2019) Impact of inhibition of the autophagy-lysosomal pathway on biomolecules carbonylation and proteome regulation in rat cardiac cells. Redox Biol. 23: 101123.  DOI: 10.1016/j.redox.2019.101123.

☆  Barayeu U, Lange M, Mendez L, Arnhold J, Shadyro OI, Fedorova M, Flemmig J. (2019) Cytochrome c auto-catalyzed carbonylation in the presence of hydrogen peroxide and cardiolipins. J Biol Chem. 294 (6):1816-1830. DOI: 10.1074/jbc.RA118.004110.

☆   Narzt MS, Nagelreiter IM, Oskolkova O, Bochkov VN, Latreille J, Fedorova M, Ni Z, Sialana FJ, Lubec G, Filzwieser M, Laggner M, Bilban M, Milder M, Tschachler E, Grillari J, Gruber F. (2019) A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids. Redox Biol. 20:467-482. DOI: 10.1016/j.redox.2018.11.006.

☆ Lange M, Ni Z, Criscuolo A, Fedorova M. (2019) Liquid Chromatography Techniques in Lipidomics Research. Chromatographia. 82 (1): 77-100. DOI: 10.1007/s10337-018-3656-4

2018

☆  Matamoros MA, Kim A, Penuelas M, Ihling C, Griesser E, Hoffmann R, Fedorova M, Frolov A, Becana M. (2018) Protein carbonylation and glycation in legume nodules. Plant Physiol. 177(4): 1510. DOI: 10.1104/pp.18.00533.

☆  Sultan CS, Saackel A, Stank A, Fleming T, Fedorova M, Hoffmann R, Wade RC, Hecker M, Wagner AH (2018) Impact of carbonylation on glutathione peroxidase-1 activity in human hyperglycemic endothelial cells. Redox Biol. 16:113. DOI: 10.1016/j.redox.2018.02.018.

☆  Ni Z, Fedorova M. (2018) Oxidized (Phospho)lipids. In Encyclopedia of Lipidomics. Springer Science+Busines Media B.V. M. Wenck (ed). DOI:10.1007/978-94-007-7864-1_183-1.

2017

☆  Colombo S, Coliva G, Kraj A, Chervet JP, Fedorova M, Domingues P, Domingues RM. (2017). Electrochemical oxidation of phosphatidylethanolamines studied by mass spectrometry. J Mass Spectrom. 53(3): 223-233. DOI: 10.1002/jms.4056.

☆  Ni Z, Angelidou G, Hoffmann R, Fedorova M. (2017) LPPtiger software for lipidome-specific prediction and identification of oxidized phospholipids from LC-MS datasets. Sci Rep, 7(1): 15138. DOI: 10.1038/s41598-017-15363-z.

☆  Fedorova M and Zarkovic N. (2017) Preface to to the Special Issue on 4-Hydroxynonenal and Related Lipid Oxidation Products. Free Radic Biol Med. 111:1. DOI: 10.1016/j.freeradbiomed.2017.05.017.

☆  Ni Z, Angelidou G, Lange M, Hoffmann R, Fedorova M. (2017) LipidHunter Identifies Phospholipids by High-Throughput Processing of LC-MS and Shotgun Lipidomics Datasets. Anal Chem. 89 (17): 8800–8807. DOI: 10.1021/acs.analchem.7b01126.

☆  Griesser E, Vemula V, Raulien N, Wagner U, Reeg S, Grune T, Fedorova M. (2017) Cross-talk between lipid and protein carbonylation in a dynamic cardiomyocyte model of mild nitroxidative stress. Redox Biol. 11: 438-455. DOI: 10.1016/j.redox.2016.12.028.

☆  Fedorova M. (2017). Diversity of protein carbonylation pathways: direct oxidation, glycoxidation and modifications by lipid peroxidation products. In Protein Carbonylation: Principles, Analysis, and Biological Implications, First Edition, Edited by Joaquim Ros. Publisher: John Wiley & Sons. pp 48-84.

2016

☆  Melo T, Domingues P, Ferreira R, Milic I, Fedorova M, Santos S, Segundo M, Domingues MR. (2016). Recent Advances on Mass Spectrometry Analysis of Nitrated Phospholipids. Anal Chem. 88(5):2622-9. DOI: 10.1021/acs.analchem.5b03407.

☆  Annibal A, Riemer T, Jovanovic O, Pohl EE, Schiller J, Hoffmann R, Fedorova M. (2016). Structural, biological and biophysical properties of glycated and glycoxidized phosphatidylethanolamines. Free Radic Biol Med. 95:293-307. DOI: 10.1016/j.freeradbiomed.2016.03.011.

2015

☆  Milic I, Kipping M, Hoffmann R, Fedorova M. (2015). Separation and characterization of oxidized isomeric lipid-peptide adducts by ion mobility mass spectrometry. J Mass Spectrom. 50(12):1386-92. DOI: 10.1002/jms.3713.

☆  Milic I, Griesser E, Vemula V, Ieda N, Nakagawa H, Miyata N, Galano JM, Oger C, Durand T, Fedorova M. (2015). Profiling and relative quantification of multiply nitrated and oxidized fatty acids. Anal Bioanall Chem. 407(19):5587-602. DOI: 10.1007/s00216-015-8766-3.

☆  Vemula V, Ni Z, Fedorova M. (2015). Fluorescence labeling of carbonylated lipids and proteins in cells using coumarin-hydrazide. Redox Biol. 23(5):195-204. DOI: 10.1016/j.redox.2015.04.006.

☆  Weber D, Ni Z, Vetter D, Hoffmann R, Fedorova M. (2015). Electrochemical oxidation of cholesterol: An easy way to generate numerous oxysterols in short reaction times. Eur J Lipid Science. DOI: 10.1002/ejlt.201500101.

☆  Ni Z, Milic I, Fedorova M. (2015). Identification of carbonylated lipids from different phospholipid classes by shotgun and LC-MS lipidomics. Anal Bioanal Chem. 407(17):5161-5163. DOI: 10.1007/s00216-015-8536-2.

☆  Anavi S, Ni Z, Tirosh O, Fedorova M. (2015). Steatosis-induced proteins adducts with lipid peroxidation products and nuclear oxidative stress in hepatocytes. Redox Biol.4:158-168. DOI: 10.1016/j.redox.2014.12.009.

☆  Milic I, Melo T, Domingues MR, Domingues P, Fedorova M. (2015). Heterogeneity of peptide adducts with carbonylated lipid peroxidation products. J Mass Spectrom.50(3):603-612. DOI: 10.1002/jms.3568.

☆  Milic I, Fedorova M. (2015). Derivatization and detection of small aliphatic and lipid-bound carbonylated lipid peroxidation products by ESI-MS. Methods Mol Biol: Advanced Protocols in Oxidative Stress III. Vol.1208: 3-20. DOI: 10.1007/978-1-4939-1441-8_1.

☆  Jovanovic O, Pashkovskaya AA, Annibal A, Vazdar M, Burchardt N, Sansone A, Gille L, Fedorova M, Ferreri C, Pohl EE. (2015). The molecular mechanism behind reactive aldehyde action on transmembrane translocations of proton and potassium ions. Free Radic Biol Med. 89: 1067-1076. DOI: 10.1016/j.freeradbiomed.2015.10.422.

☆  Annibal A, Colombo G, Milzani A, Dalle-Donne I, Fedorova M, Hoffmann R. (2015). Identification of dityrosine cross-linked sites in oxidized human serum albumin. J Chromatogr B. 1019:147-55. DOI: 10.1016/j.jchromb.2015.12.022.

☆  Augustyniak E, Adam A, Wojdyla K, Rogowska-Wrzesinska A, Willetts R, Korkmaz A, Atalay M, Weber D, Grune T, Borsa C, Gradinaru D, Bollineni RC, Fedorova M, Griffiths HR. (2015). Validation of protein carbonyl measurement: A multi-centre study. Redox Biol. 4:149-157. DOI: 10.1016/j.redox.2014.12.014.

☆  Lübker C, Urbauer RJB, Moskovitz J, Dove S, Weisemann J, Fedorova M, Urbauer JL, Seifert R. (2015). Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin. Biochem Pharmacol. 93(2):196-209. DOI: 10.1016/j.bcp.2014.11.007.

☆  Ebner J, Aşçı Arslan A, Fedorova M, Hoffmann R, Küçükçetin A, Pischetsrieder M. (2015). Peptide profiling of bovine kefir reveals 236 unique peptides released from caseins during its production by starter culture or kefir grains. J Proteomics. 117:41-57. DOI: 10.1016/j.jprot.2015.01.005.

☆  Domingues MR, Fedorova M, Domingues P. (2015). Mass spectrometry detection of protein modification by cross-reaction with lipid peroxidation products. In Reactive Oxygen Species, Lipid Peroxidation and Protein Oxidation. Publisher: Nova Science Publisher. 61-85.

☆  Spickett CM, Fedorova M, Hoffmann R, Forman HJ. (2015). An Introduction to Redox Balance and Lipid Oxidation. In Lipid Oxidation in Health and Disease. Publishers: Taylor and Francis. 1-22.

☆  Fedorova M, Hoffmann R. (2015). Oxidized lipids as damage associated molecular patterns in inflammatory responses. In Lipid Oxidation in Health and Disease. Publishers: Taylor and Francis. 151-172.

2014

☆  Bollineni RC, Hoffmann R, Fedorova M. (2014). Proteome-wide profiling of carbonylated proteins and carbonylation sites in HeLa cells under mild oxidative stress conditions. Free Radic Biol Med. 68:186-195. DOI: 10.1016/j.freeradbiomed.2013.11.030.

☆  Annibal A, Schubert K, Wagner U, Schiller J, Fedorova M. (2014). New covalent modifications of phosphatidylethanolamine by alkanals: mass spectrometry based structural characterization and biological effects. J Mass Spectrom. 49(7): 557-569. DOI: 10.1002/jms.3373.

☆  Bollineni RC, Fedorova M, Blüher M, Hoffmann R. (2014). Carbonylated plasma proteins as potential biomarkers of obesity induced type 2 diabetes mellitus. J Proteome Res. 13(11):5081-93. DOI: 10.1021/pr500324y.

☆  D’Hondt M, Fedorova M, Peng ChY, Gevaert B, Taevernier L, Hoffmann R, De Spiegeleer B. (2014). Dry heat forced degradation of buserelin peptide: Kinetics and degradant profiling. Int J Pharm. 467(1-2): 48-59. DOI: 10.1016/j.ijpharm.2014.03.043.

☆  Fedorova M, Bollineni RC, Hoffmann R. (2014). Protein carbonylation as a major hallmark of oxidative damage: update of analytical strategies. Mass Spectrom Rev. 33(2): 79-97. DOI: 10.1002/mas.21381.

2013

☆  Milic I, Hoffmann R, Fedorova M. (2013). Simultaneous detection of low and high molecular weight carbonylated compounds derived from lipid peroxidation by ESI-MS/MS. Anall Chem. 85(1): 156-162. DOI: 10.1021/ac302356z.

☆  Bollineni RC, Fedorova M, Hoffmann R. (2013). Qualitative and quantitative evaluation of derivatization reagents for different types of protein-bound carbonyl groups. Analyst. 138(17):5081-5088. DOI: 10.1039/c3an00724c.

☆  Baum F, Fedorova M, Ebner J, Hoffmann R, Pischetsrieder M. (2013). Analysis of the endogenous peptide profile of milk: identification of 248 mainly casein-derived peptides. J Proteome Res. 12(12), 5447-5462. DOI: 10.1021/pr4003273.

☆  Binelli A, Marisa I, Fedorova M, Hoffmann R, Riva C. (2013). First evidence of protein profile alteration due to the main cocaine metabolite (benzoylecgonine) in a freshwater biological model. Aquat Toxicol. 140-141, 268-278. DOI: 10.1016/j.aquatox.2013.06.013.

2012

☆  Cook SL, Zimmermann CM, Singer D, Fedorova M, Hoffmann R, Jackson GP. (2012). Comparison of CID, ETD and metastable atom-activated dissociation (MAD) of doubly and triply charged phosphorylated tau peptides. J Mass Spectrom. 47(6): 786-794. DOI: 10.1002/jms.3023.

☆  Todorovski T, Fedorova M, Hoffmann R. (2012). Identification of isomeric 5-hydroxytryptophan- and oxindolylalanine-containing peptides by mass spectrometry. J Mass Spectrom. 47(4): 453-459. DOI: 10.1002/jms.2058.

☆  Teuber K, Fedorova M, Hoffmann R, Schiller J. (2012). 2,4-Dinitrophenylhydrazine as a new reactive Matrix to analyze oxidized Phospholipids by MALDI-TOF Mass Spectrometry. Anal Letters. 45: 968-976. DOI: 10.1080/00032719.2012.670785.

☆  Milic I, Fedorova M, Teuber K, Schiller J, Hoffmann R. (2012). Characterization of oxidation products from 1-palmitoyl-2-linoleoyl-sn-glycerophosphatidylcholine in aqueous solutions and their reactions with cysteine, histidine and lysine residues. Chem Phys Lipids. 165(2): 186-196. DOI: 10.1016/j.chemphyslip.2011.12.009.

2011

☆  Todorovski T, Fedorova M, Hoffmann R. (2011). Mass spectrometric characterization of peptides containing different oxidized tryptophan residues. J Mass Spectrom. 46: 1030-1038. DOI: 10.1002/jms.1984.

☆  Bollineni RC, Hoffmann R, Fedorova M. (2011). Identification of protein carbonylation sites by two-dimensional liquid chromatography in combination with MALDI- and ESI-MS. J Proteomics. 74: 2338-2350. DOI: 10.1016/j.jprot.2011.07.002.

☆  Bollineni RC, Fedorova M, Hoffmann R. (2011). Identification of carbonylated peptides by tandem mass spectrometry using a precursor ion-like scan in negative ion mode. J Proteomics. 74: 2351-2359. DOI: 10.1016/j.jprot.2011.05.033.

☆  Ermakova II, Sakute GA, Petekhina MA, Fedorova MA, Hoffmann R, Morozov VI. (2011). Major chondroitin sulfate proteoglycans identified in L6J1 myoblast culture. Biochemistry (Mosc.). 76: 359-365. DOI: 10.1134/s0006297911030102.

☆  Todorovski T, Fedorova M, Henning L, Hoffmann R. (2011). Synthesis of peptides containing 5-hydroxytryptophan, oxindolylalanine, N-formylkynurenine and kynurenine. J Pept Sci. 17: 256-262. DOI: 10.1002/psc.1322.

2010

☆  Fedorova M, Frolov A, Hoffmann R. (2010). Fragmentation behavior of Amadori-peptides obtained by non-enzymatic glycosylation on lysine residues with ADP-ribose in tandem mass spectrometry. J Mass Spectrom. 45: 664-669. DOI: 10.1002/jms.1758.

☆  Fedorova M, Todorovski T, Kuleva N, Hoffmann R. (2010). Quantitative evaluation of tryptophan oxidation in actin and troponin I from skeletal muscles using a rat model of acute oxidative stress. Proteomics. 10: 2692-2700. DOI: 10.1002/pmic.201000147.

☆  Fedorova M, Kuleva N, Hoffmann R. (2010). Identification of cysteine, methionine and tryptophan residues of actin oxidized in vivo during oxidative stress. J Proteome Res. 9: 1598-609. DOI: 10.1021/pr901099e.

☆  Fedorova M, Kuleva N, Hoffmann R. (2010). Identification, quantification and functional aspects of skeletal muscle protein-carbonylation in vivo during acute oxidative stress. J Proteome Res. 9: 2516-26. DOI: 10.1021/pr901182r.

2009

☆  Vikhoreva NN, Vikhorev PG, Fedorova MA, Hoffmann R, Mansson A, Kuleva NV. (2009). The in vitro motility assay parameters of actin filament from Mytilus edulis exposed in vivo to copper ions. Arch Biochem Biophys. 491: 32-38. DOI: 10.1016/j.abb.2009.09.014.

☆  Fedorova M, Kuleva N, Hoffmann R. (2009). Reversible and irreversible modifications of skeletal muscle proteins in a rat model of acute oxidative stress. Biochim Biophysi Acta. 1792:1185-93. DOI: 10.1016/j.bbadis.2009.09.011.

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