About us

Fedorova Lab #LMAI

Here at “Lipid Metabolism: Analysis and Integration” (LMAI) we look at this amazing diversity of lipids by using advanced bioanalytical and computational tools. With mass spectrometry (MS) based lipidomics and epilipidomics we can take apart complex lipidomes down to the lipid molecular species level to detect and quantify even fine alterations in lipid metabolism. And then, using our computational tools we assemble this information into the detailed metabolic maps reflecting the biological status of the system.

At LMAI, we are specifically interested in:

  • Tissue lipidomes as metabolic units
  • Plasticity of lipid metabolism in stress responses
  • Lipid and lipidome quality control (at subcellular, cellular, tissue and organismal levels)
  • Concept of epilipidome, as a subset of natural lipidome formed by lipid modifications, aiming to increase regulatory capacity of biological systems

Why is it important? Lipids have huge biomedical potential in:

  • Understanding numerous metabolic disorders which emerged in pandemic proportions in the modern world. We are specifically looking at the alteration in lipid metabolism in obesity, diabetes, NAFLD and cancer.
  • When better understood, lipid metabolism can be targeted pharmacologically. Thus, we are searching for metabolic vulnerabilities which can help to combat metabolic or malignant diseases.
  • Lipids can serve as biomarkers and help to monitor the success of drug development. With MS instruments already present in clinical labs, lipids have a high potential for clinical translations as predictive, diagnostic, and prognostic biomarkers.


Palina went to Kunming, China to participate at EMBO Workshop “Membrane shaping and remodeling by proteins” and she was awarded with an “Excellent Poster Award”!

  • Fedorova Lab
  • Center for Membrane Biochemistry and Lipid Research (ZML)
    TU Dresden
  • Address: Tatzberg 47/49, 01307 Dresden

We have published our new preprint in @biorxivpreprint entitled "A targeted metabolomic method to detect epigenetically relevant metabolites". #metabolomics #epigenetics #microbiota https://www.biorxiv.org/content/10.1101/2023.11.30.569455v1
Here is a brief 🧵

🎅 One week left! Check out the list of speakers🎅
VI Omics Flash Talks Symposium
"XMass Updates 2023"
Dec 5th 2-5pm CET, Dresden
On-site and virtual
Info: http://tinyurl.com/MSDRESDEN
#Teammassspec #lipidomics #proteomics #IMS #metabolomics

Don't miss out on "Navigating cardiovascular diseases: The Lipidomics Webinar #11" featuring Dr. Dr. Olya Vvedenskaya. Join us on 12.12.2023, at 5:00 pm (CET) for an insightful session.

Sign up now 👉 https://www.lipotype.com/lipidomics-webinars/navigating-cardiovascular-diseases-insights-from-lipidomics/?utm_source=li&utm_medium=video

#Cardiovascular#Lipidomics #CVD

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  • Fedorova Lab #LMAI
  • Center of Membrane Biochemistry and Lipid Research (ZML)
  • Address: Tatzberg 47/49, 01307 Dresden
  • Copyright 2023 Fedorova Lab, LMAI
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