PräMo

  • PI:
  • Dr. Maria Fedorova
  • Consortium title:
  • Platform for Precision Medicine & Molecular Prevention
  • LMAI Project title
  • Funding period:
  • November 2025 – October 2028
  • Funding organization:
  • This project [PräMo; 100779691] is co-funded by the European Union and co-financed from the tax revenues on the basis of the budget adopted by the Saxon State

Project description:

Chronic non-communicable diseases (NCDs), including cardiometabolic, malignant, and inflammatory disorders, represent a major medical and economic burden. Early detection remains challenging because the underlying molecular processes are highly complex and may remain clinically silent for many years. In addition, reliable biomarkers for monitoring disease onset and progression are still lacking.

The Platform for Precision Medicine & Molecular Prevention (PräMo) is establishing an innovative research infrastructure to address these challenges. The Faculty of Medicine at TU Dresden contributes exceptional expertise in immunology, systems medicine, and multi-omics technologies. The interdisciplinary collaboration of the seven applicants, together with internationally leading scientists in inflammation research, immunometabolism, lipidomics, and cellular metabolism, provides a strong foundation for the development of pioneering diagnostic tools and personalized prevention strategies.

Involved LMAI members:
  • Gulyaim Sagandykova

Current projects:

Understanding dynamics of lipid metabolism and oxidation in ferroptotic cell death programme

Ferroptosis as a common underlying pathomechanism in tissue ischemia/reperfusion injury

Lipid biomarkers in hepatoellular carcinoma

Lipid mediators in hepatic stellate cell activation and fibrosis developement

Platform for precision medicine and molecular prevention

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